Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Jan;254(2):245-83.
doi: 10.1113/jphysiol.1976.sp011232.

A non-linear voltage dependent charge movement in frog skeletal muscle

W K Chandler, R F Rakowski, M F Schneider

A non-linear voltage dependent charge movement in frog skeletal muscle

W K Chandler et al. J Physiol. 1976 Jan.

Abstract

1. Voltage-clamp experiments were carried out using the three microelectrode technique. Using this method membrane current density at V1 is proportional to deltaV( = V2 - V1) where V1 and V2 are voltages at distances 1 and 21 from the end of a fibre. Voltage dependent sodium currents were blocked by tetrodotoxin, potassium by tetraethylammonium ions and rubidium. Contraction was blocked by adding sucrose, 467 mM. 2. The current deltaV (control) associated with a positive voltage step from a hyperpolarized conditioning voltage to the holding potential, -80 mV, showed two components, a capacitative transient which decayed rapidly and a maintained steady level...

PubMed Disclaimer

References

    1. Philos Trans R Soc Lond B Biol Sci. 1975 Jun 10;270(908):507-13 - PubMed
    1. J Gen Physiol. 1943 Sep 20;27(1):37-60 - PubMed
    1. J Physiol. 1972 Dec;227(1):291-312 - PubMed
    1. J Gen Physiol. 1974 Apr;63(4):460-91 - PubMed
    1. J Gen Physiol. 1974 May;63(5):625-37 - PubMed

Publication types

MeSH terms

LinkOut - more resources