Nonsterilizing immunity in avian malaria: an antibody-independent phenomenon
- PMID: 1082596
- DOI: 10.3181/00379727-151-39186
Nonsterilizing immunity in avian malaria: an antibody-independent phenomenon
Abstract
Agammaglobulinemic chickens died with fulminating parasitemias following infection with P. gallinaceum. When rescued from otherwise fatal infection by means of chloroquine therapy, B-cell deficient chickens resisted challenge infection with the same parasite. The data suggest that nonsterilizing immunity to malaria in chickens is B-cell independent.
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