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Review
. 2000 Jun;4(3):257-62.
doi: 10.1016/s1367-5931(00)00086-7.

Evolution of DNA and RNA as catalysts for chemical reactions

A Jäschke  1 , B Seelig
Affiliations
Review

Evolution of DNA and RNA as catalysts for chemical reactions

A Jäschke et al. Curr Opin Chem Biol. 2000 Jun.

Abstract

In vitro selection from combinatorial nucleic acid libraries has provided new RNA and DNA molecules that have catalytic properties. Catalyzed reactions now go far beyond self-modifying reactions of nucleic acid molecules. The future application of in vitro selected RNA and DNA catalysts in bioorganic synthesis appears promising.

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