Effect of atropine on the decay of miniature end-plate currents at the frog neuromuscular junction
- PMID: 1082783
- PMCID: PMC1666763
- DOI: 10.1111/j.1476-5381.1976.tb06965.x
Effect of atropine on the decay of miniature end-plate currents at the frog neuromuscular junction
Abstract
1 The effect of atropine on the time constant of decay (tau) of miniature end-plate currents was investigated. 2. The atropine-induced shortening of tau was accompanied by a reduction in the voltage-sensitivity of tau. 3. This effect of atropine was reversible and dose-dependent, the voltage sensitivity being abolished with high concentrations of atropine (2.5 X 10(-5)M).
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