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. 2000;88(3-4):236-9.
doi: 10.1159/000015558.

Genomic organization, proposed alternative splicing mechanisms, and RNA editing structure of GRIK1

A Barbon  1 , S Barlati
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Genomic organization, proposed alternative splicing mechanisms, and RNA editing structure of GRIK1

A Barbon et al. Cytogenet Cell Genet. 2000.

Abstract

In the present study, we report the genomic reconstruction of the glutamate receptor GluR5 gene (GRIK1, alias GLUR5; 402 kb) by the use of the data available in public databases. This analysis allowed characterization of the exon-intron boundaries, identification of the gene promoter region, presentation of the putative complete sequences of two GluR5 mRNA isoforms, and definition of the structure of GluR5 pre-mRNA surrounding the Q/R editing site.

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