Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2000 Mar-Apr;63(2):54-6.

[The hemorheological effects of Lychnis chalcedonica L. extracts]

[Article in Russian]
M B Plotnikov  1 , O I Aliev, A S Vasil'ev, M Iu Maslov, L N Zibareva, S E Dmitruk, G I Kalinkina
Affiliations
  • PMID: 10834096
Comparative Study

[The hemorheological effects of Lychnis chalcedonica L. extracts]

[Article in Russian]
M B Plotnikov et al. Eksp Klin Farmakol. 2000 Mar-Apr.

Abstract

The hemorrheological effects of extracts from Maltese cross campion (Lychnis chalcedonica L.) prepared using 40% (I) and 70% (II) aqueous ethanol solutions were studied in vitro in comparison with tanakan on the model of high blood viscosity syndrome. Under the hyperthermia conditions, extracts I and II at a concentration of 1 x 10(-5) g/ml limited the growth of blood viscosity and thrombocyte aggregation and the drop in thrombocyte deformability. The effects of both extracts were comparable to those of tanakan. Prolonged (5 days) administration of extract I (daily dose, 150 mg/kg p.o) in rats with arterial hypertension (SHR) decreased the viscosity of whole blood and plasma, reduced the concentration of fibrinogen, and increased the deformability of erythrocytes. No reliable effects of the extracts in vivo upon the erythrocyte aggregation and hematocrit were observed.

PubMed Disclaimer

Publication types