Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2000 Mar-Apr;63(2):63-6.

[The dynamics of antigen-antibody complex formation in the presence of iodine-containing diagnostic agents]

[Article in Russian]
I V Shabunin  1 , V O Panov, V V Avdienko, N L Shimanovskiĭ
Affiliations
  • PMID: 10834099

[The dynamics of antigen-antibody complex formation in the presence of iodine-containing diagnostic agents]

[Article in Russian]
I V Shabunin et al. Eksp Klin Farmakol. 2000 Mar-Apr.

Abstract

A mathematical model is proposed to describe the antigen-antibody complex formation under the immunoassay conditions, which allows the antibody-antigen affinity to be evaluated. In particular, it is established that the dissociation constant of the antigen-antibody complex (for antibodies to a tuberculous Mycobacterium) confidently increases (p > 0.95) in the following sequence of diagnostic kits: omnipak > Ultravist > melitrast > Triombrast. The method suggested for analysis of the influence of xenobiotics upon the antigen-antibody reaction can be used to reveal their possible side effects on the antigen-antibody complex formation in any particular case.

PubMed Disclaimer

Publication types