Review
doi: 10.1515/CCLM.2000.020.
The genetics of multiple sclerosis
Affiliations
- PMID: 10834400
- DOI: 10.1515/CCLM.2000.020
Item in Clipboard
Review
The genetics of multiple sclerosis
Clin Chem Lab Med.
2000 Feb.
Abstract
Classical genetic studies involving the analysis of pedigrees and recurrence risk within families have defined the extent to which genetic factors contribute to the aetiology of multiple sclerosis. Limited progress has been made in identifying the number and topography of genetic loci contributing to susceptibility through molecular investigation either of candidate genes or the whole genome using microsatellite and single nucleotide polymorphisms.
Similar articles
-
Progress in deciphering the genetics of multiple sclerosis.Curr Opin Neurol. 2003 Jun;16(3):253-8. doi: 10.1097/01.wco.0000073924.19076.bb. Curr Opin Neurol. 2003. PMID: 12858059 Review.
-
Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium.Hum Mol Genet. 2007 Aug 15;16(16):1951-8. doi: 10.1093/hmg/ddm142. Epub 2007 Jun 20. Hum Mol Genet. 2007. PMID: 17584771
-
An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: a report from the Canadian Collaborative Study Group.Hum Mol Genet. 2004 May 15;13(10):1005-15. doi: 10.1093/hmg/ddh123. Epub 2004 Apr 6. Hum Mol Genet. 2004. PMID: 15069025
-
Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis.Tissue Antigens. 2004 Mar;63(3):237-47. doi: 10.1111/j.0001-2815.2004.00173.x. Tissue Antigens. 2004. PMID: 14989713
-
The genetics of multiple sclerosis.J Neurovirol. 2000 May;6 Suppl 2:S5-9. J Neurovirol. 2000. PMID: 10871776 Review.
Cited by
-
Detection of infectious agents in brain of patients with acute hemorrhagic leukoencephalitis.J Neurovirol. 2002 Oct;8(5):439-46. doi: 10.1080/13550280260422749. J Neurovirol. 2002. PMID: 12402170
-
The Potential Role of T Helper Cell 22 and IL-22 in Immunopathogenesis of Multiple Sclerosis.Innov Clin Neurosci. 2016 Aug 1;13(7-8):30-6. eCollection 2016 Jul-Aug. Innov Clin Neurosci. 2016. PMID: 27672486 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
