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Review
. 2000 Jun;8(6):274-8.
doi: 10.1016/s0966-842x(00)01762-5.

The bactericidal action of penicillin: new clues to an unsolved mystery

K W Bayles  1
Affiliations
Review

The bactericidal action of penicillin: new clues to an unsolved mystery

K W Bayles. Trends Microbiol. 2000 Jun.

Abstract

The Staphylococcus aureus lrgAB operon was recently shown to inhibit extracellular murein hydrolase activity and increase tolerance to penicillin. Further characterization of this operon could provide novel insight into the dynamics of S. aureus cell wall metabolism and the mechanism of penicillin-induced lethality.

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