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. 1976 Jun 1;143(6):1528-33.
doi: 10.1084/jem.143.6.1528.

Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines

P Ralph, M A Moore, K Nilsson

Lysozyme synthesis by established human and murine histiocytic lymphoma cell lines

P Ralph et al. J Exp Med. .

Abstract

A human cell line established in culture from a histiocytic lymphoma patient synthesizes and secretes the monocyte-granulocyte specific enzyme lysozyme. 18 other human cell lines with characteristics of T-lymphocyte, B-lymphocyte, Burkitt's lymphoma, non-Burkitt's lymphoma, myeloma, and bone marrow epithelial cells were not associated with lysozyme. Among murine cell lines, lysozyme was produced by (a) three histiocytic lymphoma or macrophage lines, which mediate antibody-dependent phagocytosis and cytolysis; (b) myelomonocytic leukemia line which also secretes myeloid colony-stimulating factor; and (c) a spontaneous lymphoma and an Abelson leukemia virus-induced lymphoma. Lysozyme-negative lines include another Abelson lymphoma, myelomas, T lymphomas, and mastocytoma.

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References

    1. Eur J Immunol. 1975 Aug;5(8):518-26 - PubMed
    1. Cancer. 1974 Dec;34(6):1851-72 - PubMed
    1. Int J Cancer. 1974 Jun 15;13(6):808-23 - PubMed
    1. J Natl Cancer Inst. 1968 Apr;40(4):771-821 - PubMed
    1. Biochem Biophys Res Commun. 1974 Dec 23;61(4):1268-75 - PubMed

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