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. 2000 Jun;82(11):1892-4.
doi: 10.1054/bjoc.1999.1212.

Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese

H Saeki  1 , S Ohno, K Araki, A Egashira, H Kawaguchi, Y Ikeda, M Morita, K Kitamura, K Sugimachi
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Free PMC article

Alcohol consumption and cigarette smoking in relation to high frequency of p53 protein accumulation in oesophageal squamous cell carcinoma in the Japanese

H Saeki et al. Br J Cancer. 2000 Jun.
Free PMC article

Abstract

We investigated levels of p53 protein expression in Japanese patients with oesophageal squamous cell carcinoma. A significantly larger proportion of heavy alcohol drinkers and cigarette smokers was evident in the p53-positive group. The combination of drinking and smoking was associated with a high frequency of p53 protein accumulation.

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