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Comparative Study
. 2000 May 15;10(10):1043-5.
doi: 10.1016/s0960-894x(00)00159-1.

Antimycobacterial activity of ionic fullerene derivatives

S Bosi  1 , T Da Ros, S Castellano, E Banfi, M Prato
Affiliations
Comparative Study

Antimycobacterial activity of ionic fullerene derivatives

S Bosi et al. Bioorg Med Chem Lett. .

Abstract

Positively charged fullerene derivatives, moderately soluble in water:DMSO 9:1, have been tested using three strains of Mycobacterium spp. Some compounds inhibit the growth of Mycobacterium tuberculosis, a human clinical isolate, particularly virulent and resistant, at doses as low as 5 microg/mL.

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