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. 2000 May;63(5):707-9.
doi: 10.1021/np9904511.

Mycalamide D, a new cytotoxic amide from the New Zealand marine sponge Mycale species

L M West  1 , P T Northcote, K A Hood, J H Miller, M J Page
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Mycalamide D, a new cytotoxic amide from the New Zealand marine sponge Mycale species

L M West et al. J Nat Prod. 2000 May.

Abstract

A new mycalamide, mycalamide D (3), has been isolated from the New Zealand marine sponge Mycale sp. This new metabolite, in which the C13-O-methyl group of mycalamide A (1) is replaced by a hydrogen atom, was found to be cytotoxic to a range of mammalian cell lines, with a potency approximately 20-fold less than that of 1.

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