QTL fine mapping, in extreme samples of finite populations, for complex traits with familial correlation due to polygenes
- PMID: 10848499
- PMCID: PMC1287090
- DOI: 10.1086/302977
QTL fine mapping, in extreme samples of finite populations, for complex traits with familial correlation due to polygenes
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Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus.Am J Hum Genet. 1998 Nov;63(5):1531-40. doi: 10.1086/302114. Am J Hum Genet. 1998. PMID: 9867708 Free PMC article.
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QTL fine mapping by measuring and testing for Hardy-Weinberg and linkage disequilibrium at a series of linked marker loci in extreme samples of populations.Am J Hum Genet. 2000 Mar;66(3):1027-45. doi: 10.1086/302804. Am J Hum Genet. 2000. PMID: 10712216 Free PMC article.
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Inflated false-positive rates in Hardy-Weinberg and linkage-equilibrium tests are due to sampling on the basis of rare familial phenotypes in finite populations.Am J Hum Genet. 2000 Jul;67(1):258-9. doi: 10.1086/302964. Am J Hum Genet. 2000. PMID: 10848498 Free PMC article. No abstract available.
References
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- Feder JN, Gnirke A, Thomas W, Tsuchihasi Z (1996) A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 13:399–408 - PubMed
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