Melanoma and other skin cancers in circumpolar areas
- PMID: 10850007
Melanoma and other skin cancers in circumpolar areas
Abstract
During the recent decades, the thickness of the ozone layer over the northern hemisphere has declined by 10 to 40 percent during the winter and spring months. Since ozone is the major barrier protecting the earth from dangerous short wave UV-radiation (UVB), the depletion in the ozone layer consequently increases the amount of UV-radiation reaching the earth's surface. As a rule a 10 percent reduction in the ozone layer causes ca. 20% increase in UV-radiation and a 40% increase in skin cancers. Thus relatively minor changes in ozone layer thickness may a have marked impact on the health of humans. Skin cancer is the most common cancer in humans, i.e. in Finland about 4000 new basal cell carcinomas, 700 other skin cancers, mostly spinous cell carcinomas and 500 melanomas occur yearly. Up to recent years the incidence of skin cancers has steadily increased in northern countries. As an explanation, changes in sunbathing habits have been suggested to play a central role. Due to the high mortality rate in melanoma, and marked morbidity in other skin cancers, it is important to try to prevent skin cancers and inform the public about the risks of excessive sun exposure, and of the ways in which the skin can be protected. Proper clothing and use of sunscreens have been shown to reduce the incidence of both melanomas and other skin cancers. Furthermore, it is important to identify those at high risk for acquiring skin cancers, like individuals with type 1 skin character (fair skin which burns easily), or numerous dysplastic nevi, or a family history of skin cancers.
Similar articles
-
The consequences for human health of stratospheric ozone depletion in association with other environmental factors.Photochem Photobiol Sci. 2015 Jan;14(1):53-87. doi: 10.1039/c4pp90033b. Photochem Photobiol Sci. 2015. PMID: 25383760
-
[Disappearance of the ozone layer and skin cancer: attempt at risk assessment].Hautarzt. 1993 Feb;44(2):63-8. Hautarzt. 1993. PMID: 8449695 Review. German.
-
[UV exposure, skin cancer and decrease in the ozone layer].Ther Umsch. 1993 Dec;50(12):804-7. Ther Umsch. 1993. PMID: 8171400 German.
-
The human health effects of ozone depletion and interactions with climate change.Photochem Photobiol Sci. 2011 Feb;10(2):199-225. doi: 10.1039/c0pp90044c. Epub 2011 Jan 20. Photochem Photobiol Sci. 2011. PMID: 21253670 Review.
-
Ultraviolet radiation and skin cancer.Int J Dermatol. 2010 Sep;49(9):978-86. doi: 10.1111/j.1365-4632.2010.04474.x. Int J Dermatol. 2010. PMID: 20883261 Review.
Cited by
-
Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase eta.Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12093-8. doi: 10.1073/pnas.2134223100. Epub 2003 Oct 3. Proc Natl Acad Sci U S A. 2003. PMID: 14527996 Free PMC article.
-
Changing Trends in Melanoma Incidence and Decreasing Melanoma Mortality in Hungary Between 2011 and 2019: A Nationwide Epidemiological Study.Front Oncol. 2021 Feb 12;10:612459. doi: 10.3389/fonc.2020.612459. eCollection 2020. Front Oncol. 2021. PMID: 33643913 Free PMC article.
-
Skin cancer incidence in rural workers at a reference hospital in western Paraná.An Bras Dermatol. 2019 Mar-Apr;94(2):157-163. doi: 10.1590/abd1806-4841.20197335. Epub 2019 May 9. An Bras Dermatol. 2019. PMID: 31090820 Free PMC article.
-
Requirement of DNA polymerase eta for error-free bypass of UV-induced CC and TC photoproducts.Mol Cell Biol. 2001 Jan;21(1):185-8. doi: 10.1128/MCB.21.1.185-188.2001. Mol Cell Biol. 2001. PMID: 11113193 Free PMC article.
-
Ultraviolet light screen using cholesteric liquid crystal capsules on the basis of selective reflection.RSC Adv. 2021 Jul 22;11(41):25471-25476. doi: 10.1039/d1ra03499e. eCollection 2021 Jul 19. RSC Adv. 2021. PMID: 35478880 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Medical
Research Materials