Review
doi: 10.1016/s0959-4388(00)00093-3.
Molecular determinants of presynaptic active zones
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- PMID: 10851173
- DOI: 10.1016/s0959-4388(00)00093-3
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Review
Molecular determinants of presynaptic active zones
Curr Opin Neurobiol.
2000 Jun.
Abstract
The presynaptic cytoskeletal matrix (cytomatrix) assembled at active zones has been implicated in defining neurotransmitter release sites. Munc13, Rim, Bassoon and Piccolo/Aczonin are recently identified presynaptic cytomatrix proteins. These multidomain proteins are thought to organize the exocytotic and endocytotic machinery precisely at active zones.
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