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. 1975;52(4-6):747-51.

The meaning of persistent infections in nature

The meaning of persistent infections in nature

C A Mims. Bull World Health Organ. 1975.

Abstract

Viruses that cause persistent infections maintain themselves more effectively in nature than those causing acute and limited infections. There is a tendency for persistent viruses to evolve towards a state of minimal pathogenicity in the host. Vertical transmission, with integration of viral into host genome, represents the state of perfect parasitism.

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