Secretion of Ia antigens by a subpopulation of T cells which are Ly-1+, Ly-2-, and Ia-
- PMID: 1085342
- PMCID: PMC2190400
- DOI: 10.1084/jem.144.3.847
Secretion of Ia antigens by a subpopulation of T cells which are Ly-1+, Ly-2-, and Ia-
Abstract
It was found that Ia antignes are rapidly secreted by a subpopulation of splenic T lymphocytes which are nonadherent and which express the surface phenotype Ly-1+, Ly-2-, and Ia-. Secretion of the Ia antigens was a metabolically active process which was inhibited by sodium azide and by Pactamycin, an inhibitor of protein synthesis.
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