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Review
. 2000 Spring;63(1):1-12.
doi: 10.1080/00332747.2000.11024887.

Low use of analgesics in Alzheimer's disease: possible mechanisms

E J Scherder  1
Affiliations
Review

Low use of analgesics in Alzheimer's disease: possible mechanisms

E J Scherder. Psychiatry. 2000 Spring.

Abstract

This article discusses three possible mechanisms that might underlie the often observed low use of nonsteroidal anti-inflammatory drugs (NSAIDs) and other analgesics in patients with Alzheimer's disease (AD), compared with nondemented elderly: (a) AD patients are progressively less able to communicate about pain; (b) AD patients suffer from fewer painful conditions than nondemented elderly subjects; and (c) considering the neuropathology, AD patients might actually experience pain to a lesser extent. Suggestions for future pain assessment in AD are made.

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