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Comparative Study
. 2000 Apr;23(4):500-3.
doi: 10.2337/diacare.23.4.500.

Evaluation of an electrochemical sensor for measuring blood ketones

H A Byrne  1 , K L Tieszen, S Hollis, T L Dornan, J P New
Affiliations
Comparative Study

Evaluation of an electrochemical sensor for measuring blood ketones

H A Byrne et al. Diabetes Care. 2000 Apr.

Abstract

Objective: To evaluate the performance of a hand-held ketone sensor that is able to measure blood beta-hydroxybutyrate (beta-HBA) concentrations within 30 s in patients with diabetic ketoacidosis (DKA) and patients who attend a weight management clinic.

Research design and methods: Two groups of patients were studied: 19 patients admitted with DKA and 156 patients attending a weight management clinic. Paired capillary and venous whole blood samples were measured using the ketone sensor and also using an enzymatic laboratory reference method.

Results: The ketone sensor accurately measured beta-HBA concentrations in patients with DKA (limits of agreement -0.9 to + 1.0 mmol/l) or starvation-induced ketonemia (limits of agreement -0.5 to +0.5 mmol/l).

Conclusions: This ketone sensor accurately measures whole blood beta-HBA concentrations within 30 s.

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