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Review
. 2000 Apr;2(5):533-42.
doi: 10.1016/s1286-4579(00)00312-9.

Bacterial ureases in infectious diseases

R A Burne  1 , Y Y Chen
Affiliations
Free article
Review

Bacterial ureases in infectious diseases

R A Burne et al. Microbes Infect. 2000 Apr.
Free article

Abstract

Ureases are multi-subunit, nickel-containing enzymes that catalyze the hydrolysis of urea to carbon dioxide and ammonia. This brief review discusses the biochemistry and genetics of bacterial ureases and outlines the roles of urea metabolism in microbial ecology and pathogenesis of some of the principle ureolytic species affecting human health.

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