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Case Reports
. 2000 May-Jun;16(3):177-8.
doi: 10.1002/1520-7560(0000)9999:9999<::aid-dmrr100>3.0.co;2-5.

Non-specific viral infections as possible synchronising events of the manifestation of type 1 diabetes

H E Wasmuth  1 , G Hess, C Viergutz, H R Henrichs, S Martin, H Kolb
Affiliations
Case Reports

Non-specific viral infections as possible synchronising events of the manifestation of type 1 diabetes

H E Wasmuth et al. Diabetes Metab Res Rev. 2000 May-Jun.

Abstract

Four cases of simultaneous manifestation of Type 1 diabetes in two members of the same household are reported. In all cases, a flu-like infection preceded diabetes onset. Surprisingly, despite simultaneous development of insulin dependency, insulin requirements were strikingly different at 3 months in all cases. These observations suggest that increased insulin resistance during infection may cause insulin deficiency in individuals with widely varying residual beta cell activity.

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