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. 1976;52(5 Suppl):112-7.

Antithymocyte antiserum therapy in myasthenia gravis

B Pirofsky, R H Reid, E J Bardana Jr, R L Baker
  • PMID: 1087017

Antithymocyte antiserum therapy in myasthenia gravis

B Pirofsky et al. Postgrad Med J. 1976.

Abstract

The therapeutic effect of goat anti-human thymocyte antiserum globulin (ATG) was assessed in 10 patients with myasthenia gravis. Prolonged, low dose therapy was used with 1-0--1-6 grams protein administered intramuscularly over a 28-73 day period. Varying degrees of therapeutic response were noted in 8 patients. Fllow-up examinations for over 5 years have been maintained and relapse rates determined. The clinical criteria for aptients selection and characteristics of therapeutic response are presented.

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