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. 1979 Mar 14;61(1):39-41.
doi: 10.1007/BF00426808.

Inhibition-mediating dopamine receptors and the control of intracranial reward

R J Katz
Free article

Inhibition-mediating dopamine receptors and the control of intracranial reward

R J Katz. Psychopharmacology (Berl). .
Free article

Abstract

A receptor selective agonist and antagonist of inhibition-mediating dopamine receptors (type II receptors) produced significant and dose-related alterations in bar-pressing for intracranial reward. Receptor inhibition by piribedil increased responding for reward while receptor activation by 3,4-dihydroxyphenylamino-2-imidazoline reduced responding. Inhibition-mediating receptors may therefore play a role opposite to classic excitation-mediating receptors in controlling reward.

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