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. 1976 Sep;6(9):663-5.
doi: 10.1002/eji.1830060914.

T lineage lymphocytes in nude mice born from homozygous nu/nu parents

F Loor, H Amstutz, L B Hägg, K S Mayor, G E Roelants

T lineage lymphocytes in nude mice born from homozygous nu/nu parents

F Loor et al. Eur J Immunol. 1976 Sep.

Abstract

T lineage cells are found in the spleen of neonatal nu/nu mice born from nu/nu x nu/nu matings, and also in old, healthy nude mice obtained from the usual nu/+ x nu/nu matings. Their presence in neonatal nude mice which were never in contact with mother or normal littermate thymus products shows that commitment of stem cells towards the T lineage does not require the influence of the thymus.

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