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. 1976 Dec 1;144(6):1683-8.
doi: 10.1084/jem.144.6.1683.

Spontaneous redistribution of surface immunoglobulin in the motile B lymphocyte

G F Schreiner, J Braun, E R Unanue

Spontaneous redistribution of surface immunoglobulin in the motile B lymphocyte

G F Schreiner et al. J Exp Med. .

Abstract

This paper reports that B cells undergoing translatory motion spontaneously segregate their surface Ig to one portion of their plasma membrane. The spontaneous redistribution of surface Ig was found to be: (a) selective, concanavalin A-dependent on translatory motion and energy metabolism. Abundant B cells undergoing motility were found after cultures in lipopolysaccharide or trypsin, or after brief exposure to cholinergic drugs.

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References

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