Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Mar 22;61(2):197-202.
doi: 10.1007/BF00426736.

Plasmatic renin activity in patients treated with L-dopa and inhibitor of dopa decarboxylase (IDC)

H Allain, J Van den Driessche, D Bentue-Ferrer, J M Reymann, D Pape, M Madigand

Plasmatic renin activity in patients treated with L-dopa and inhibitor of dopa decarboxylase (IDC)

H Allain et al. Psychopharmacology (Berl). .

Abstract

Plasmatic renin activity (PRA) was studied in patients receiving L-dopa, together with a decarboxylase inhibitor, at rest times and after periods of physical exertion. Although we can superimpose the results from unrelated Parkinson's disease patients on those of the control group, the results are inversed in stabilized patients (lowered PRA) and dyskinetic patients (increased PRA). There is a definite correlation between the increase in PRA and intensity of the dyskinesia. Dosage is the only other factor differentiating the two groups of Parkinsonians treated. The figures relative to arterial pressure are studied in the various groups.

PubMed Disclaimer

References

    1. Psychopharmacologia. 1976 Feb 2;45(3):243-54 - PubMed
    1. Pharmacol Rev. 1973 Sep;25(3):415-49 - PubMed
    1. JAMA. 1973 Jun 25;224(13):1726-9 - PubMed
    1. Rev Neurol (Paris). 1977 May;133(5):297-308 - PubMed
    1. JAMA. 1970 Jul 6;213(1):83-5 - PubMed

LinkOut - more resources