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Review
. 2000 Jul 4;133(1):40-54.
doi: 10.7326/0003-4819-133-1-200007040-00008.

Pharmacologic treatment of heroin-dependent patients

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Review

Pharmacologic treatment of heroin-dependent patients

P G O'Connor et al. Ann Intern Med. .

Abstract

Patients with heroin dependence frequently present to internists and other physicians for heroin-related medical, psychiatric, and behavioral health problems and often seek help with reducing their heroin use. Thus, physicians should be familiar with the identification and diagnosis of heroin dependence in their patients and be able to initiate treatment of heroin dependence both directly and by referral. Recent research has provided much information concerning effective pharmacologically based treatment approaches for managing opioid withdrawal and helping patients to remain abstinent Methadone maintenance and newer approaches using L-alpha acetylmethadol and buprenorphine seem to be particularly effective in promoting relapse prevention. Although these treatments are currently provided in special drug treatment settings, recent and ongoing research indicates that the physician's office may be an effective alternative site for these treatments.

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  • Indinavir, zidovudine, lamivudine: 3-year follow-up.
    Dworkin MS, Wan PT. Dworkin MS, et al. Ann Intern Med. 2001 Jan 16;134(2):165. doi: 10.7326/0003-4819-134-2-200101160-00019. Ann Intern Med. 2001. PMID: 11177322 No abstract available.
  • Treatment of heroin dependence.
    Hyman MH. Hyman MH. Ann Intern Med. 2001 Apr 17;134(8):714-5. doi: 10.7326/0003-4819-134-8-200104170-00016. Ann Intern Med. 2001. PMID: 11304111 No abstract available.

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