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. 2000 Jul;38(7):2774-7.
doi: 10.1128/JCM.38.7.2774-2777.2000.

Characterization of glycopeptide-resistant enterococcus faecium (GRE) from broilers and pigs in Denmark: genetic evidence that persistence of GRE in pig herds is associated with coselection by resistance to macrolides

F M Aarestrup  1
Affiliations

Characterization of glycopeptide-resistant enterococcus faecium (GRE) from broilers and pigs in Denmark: genetic evidence that persistence of GRE in pig herds is associated with coselection by resistance to macrolides

F M Aarestrup. J Clin Microbiol. 2000 Jul.

Abstract

Glycopeptide-resistant enterococci (GRE) from broilers and pigs were characterized to investigate the background for the persistence of GRE in pig herds. All porcine isolates belonged to closely related pulsed-field gel electrophoretic (PFGE) types, with the ermB and vanA genes located on the same transferable genetic element. Broiler isolates belonged to different PFGE types. The persistence of GRE in Danish pig herds after the ban of glycopeptides may be explained by the genetic link between ermB and vanA and coselection by use of macrolides for treatment and growth promotion.

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Figures

FIG. 1
FIG. 1
Representative SmaI PFGE types observed among glycopeptide-resistant E. faecium isolates from broilers in Denmark.
FIG. 2
FIG. 2
Representative SmaI PFGE types observed among glycopeptide-resistant E. faecium isolates from pigs in Denmark and transfer of glycopeptide resistance to E. faecium BM4105RF. Lanes 1 to 6, isolates from pigs; lane 7, E. faecium BM4105RF; lanes 8 to 13, glycopeptide-resistant transformants of E. faecium BM4105RF corresponding to isolates in lanes 1 to 6; lanes 1, 2, 4, and 6, the most common PFGE type from pigs; lane 3, a closely related type, represented by four isolates; lane 5, another closely related type, represented by three isolates.
See this image and copyright information in PMC

References

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