[Receptors for murine red blood cells on normal lymphocytes and in chronic lymphocytic leukemia]

Abstract

The ability of unfractionated and purified B and T peripheral lymphocytes to form rosettes EAC and E with sheep and mouse red blood cells was assessed in thirty healthy controls and in five patients with chronic lymphocytic leukaemia. E mouse rosettes is a marker of B cells in man and its percentage in peripheral blood lymphocytes is 9.3% in normal subjects on the contrary patients with CLL had a high rosette count with mouse red blood cells (mean 57%) and a low count with sheep red blood cells (mean 13.7%).