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Case Reports
. 2000 Aug;164(2):385-7.

Transperineal magnetic resonance image guided prostate biopsy

A V D'Amico  1 , C M Tempany, R Cormack, N Hata, M Jinzaki, K Tuncali, M Weinstein, J P Richie
Affiliations
  • PMID: 10893591
Case Reports

Transperineal magnetic resonance image guided prostate biopsy

A V D'Amico et al. J Urol. 2000 Aug.

Abstract

Purpose: We report the findings of a transperineal magnetic resonance image (MRI) guided biopsy of the prostate in a man with increasing prostate specific antigen who was not a candidate for a transrectal ultrasound guided biopsy.

Materials and methods: Using an open configuration 0.5 Tesla MRI scanner and pelvic coil, a random sextant sample was obtained under real time MRI guidance from the peripheral zone of the prostate gland as well as a single core from each MRI defined lesion. The patient had previously undergone proctocolectomy for ulcerative colitis and, therefore, was not a candidate for transrectal ultrasound guided biopsy. Prior attempts to make the diagnosis of prostate cancer using a transurethral approach were unsuccessful.

Results: The random sextant samples contained benign prostatic hyperplasia, whereas Gleason grade 3 + 3 = 6 adenocarcinoma was confirmed in 15% and 25% of the 2 cores obtained from the MRI targeted specimens of 2 defined lesions. The procedure was well tolerated by the patient.

Conclusions: Transperineal MRI guided biopsy is a new technique that may be useful in detecting prostate cancer in men with increasing prostate specific antigen who are not candidates for transrectal ultrasound guided biopsy.

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