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. 1975 Feb;11(2):334-6.
doi: 10.1128/iai.11.2.334-336.1975.

Test for enterotoxigenic Escherichia coli using Y-1 adrenal cells in miniculture

D A Sack, R B Sack

Test for enterotoxigenic Escherichia coli using Y-1 adrenal cells in miniculture

D A Sack et al. Infect Immun. 1975 Feb.

Abstract

A rapid, potentially clinically useful test for detection of enterotoxigenic Escherichia coli is described. Whole bacterial cultures of enterotoxigenic E. coli, when briefly exposed to Y1 adrenal cells in tissue miniculture, effect a rounding response in the tissue culture that can be discerned at 18 to 24 h. The tissue culture technique agreed with the rabbit ileal loop in all 58 enterotoxigenic and 52 non-enterotoxigenic E. coli strains tested.

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References

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    1. J Infect Dis. 1971 Apr;123(4):378-85 - PubMed
    1. J Infect Dis. 1974 Jan;129(1):1-9 - PubMed
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