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Review
. 2000 Jul;106(2):165-9.
doi: 10.1172/JCI10582.

Signaling pathways in insulin action: molecular targets of insulin resistance

J E Pessin  1 , A R Saltiel
Affiliations
Review

Signaling pathways in insulin action: molecular targets of insulin resistance

J E Pessin et al. J Clin Invest. 2000 Jul.
No abstract available

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Figures

Figure 1
Figure 1
Schematic model indicating the presence of two potential insulin receptor–dependent signal transduction pathways. In this model, insulin stimulation results in the activation of a PI 3-kinase–dependent pathway that is necessary but not sufficient to induce GLUT4 translocation. In parallel, the insulin receptor activates an additional pathway leading to Cbl tyrosine phosphorylation through its interaction with the CAP protein. Syn4, syntaxin 4; PI3-K, PI 3-kinase.
See this image and copyright information in PMC

References

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