Review
doi: 10.1016/s0162-3109(00)80296-9.
Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1
Affiliations
- PMID: 10904110
- DOI: 10.1016/s0162-3109(00)80296-9
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Review
Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1
Immunopharmacology.
2000 Aug.
Abstract
The Regulators of Complement Activation (RCA) are a fascinating group of proteins that play important roles in innate and acquired immunity. In this review, we examine structure-function aspects of three membrane-bound RCA proteins and discuss the unique impact of their genetic organization on their evolution.
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