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Review
. 2000 Aug;49(1-2):103-16.
doi: 10.1016/s0162-3109(00)80296-9.

Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1

D Hourcade  1 , M K Liszewski, M Krych-Goldberg, J P Atkinson
Affiliations
Review

Functional domains, structural variations and pathogen interactions of MCP, DAF and CR1

D Hourcade et al. Immunopharmacology. 2000 Aug.

Abstract

The Regulators of Complement Activation (RCA) are a fascinating group of proteins that play important roles in innate and acquired immunity. In this review, we examine structure-function aspects of three membrane-bound RCA proteins and discuss the unique impact of their genetic organization on their evolution.

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