Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2000 Jul;71(1-2):1-21.
doi: 10.1016/s0378-8741(00)00212-9.

The traditional uses, chemical constituents and biological activities of Plantago major L. A review

Affiliations
Review

The traditional uses, chemical constituents and biological activities of Plantago major L. A review

A B Samuelsen. J Ethnopharmacol. 2000 Jul.

Abstract

Plantago major L. leaves have been used as a wound healing remedy for centuries in almost all parts of the world and in the treatment of a number of diseases apart from wound healing. These include diseases related to the skin, respiratory organs, digestive organs, reproduction, the circulation, against cancer, for pain relief and against infections. P. major contains biologically active compounds such as polysaccharides, lipids, caffeic acid derivatives, flavonoids, iridoid glycosides and terpenoids. Alkaloids and some organic acids have also been detected. A range of biological activities has been found from plant extracts including wound healing activity, anti-inflammatory, analgesic, antioxidant, weak antibiotic, immuno modulating and antiulcerogenic activity. Some of these effects may attribute to the use of this plant in folk medicine.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Alkaloids in P. major L. Indicain: R=CHO; plantagonin: R=COOH.
Fig. 2
Fig. 2
Caffeic acid derivatives in P. major L. (A) Caffeic acid, (B) chlorogenic acid, (C) Plantamajoside R=Glc, acteoside R=Rha.
Fig. 3
Fig. 3
Iridoid glycosides from P. major L.

References

    1. Ahmad M.S., Ahmad M.U., Osman S.M. A new hydroxyolefinic acid from Plantago major seed oil. Phytochemistry. 1980;19:217–2139.
    1. Ahmad M., Rizwani G.H., Aftab K., Ahmad U.V., Gilani A.H., Ahmad S.P. Acteoside: a new antihypertensive drug. Phytotherapy Research. 1995;9:525–527.
    1. Ahmed Z.F., Rizk A.M., Hammouda F.M. Phytochemical studies of egyptian Plantago species (Glucides) Journal of Pharmaceutical Sciences. 1965;54:1060–1062. - PubMed
    1. Ahmed Z.F., Hammouda F.M., Rizk A.M., Wassel G.M. Phyochemical studies of egyptian Plantago species. Planta Medica. 1968;4:404–410. - PubMed
    1. Andary C., Wylde R., Laffite C., Privat G., Winternitz F. Structures of verbascoside and oroban choside, caffeic acid sugar esters from Orobanche rapum-genistae. Phytochemistry. 1982;21:1123–1127.

LinkOut - more resources