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. 2000 May 13;355(9216):1696-7.
doi: 10.1016/s0140-6736(00)02246-7.

Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease

E Adalsteinsson, E V Sullivan, N Kleinhans, D M Spielman, A Pfefferbaum

Longitudinal decline of the neuronal marker N-acetyl aspartate in Alzheimer's disease

E Adalsteinsson et al. Lancet. .

Abstract

In patients with Alzheimer's disease, but not in health controls, longitudinal magnetic resonance spectroscopy shows a striking decline in the neuronal marker, N-acetyl aspartate, despite little decline in underlying grey-matter volume.

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