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. 1979 Apr;38(2):137-40.
doi: 10.1136/ard.38.2.137.

Whole body elemental composition during drug treatment of rheumatoid arthritis: a preliminary study

A C Kennedy, K Boddy, E D Williams, A T Elliott, I Harvey, I Holloway, J K Haywood

Whole body elemental composition during drug treatment of rheumatoid arthritis: a preliminary study

A C Kennedy et al. Ann Rheum Dis. 1979 Apr.

Abstract

Thirty-two female patients with rheumatoid arthritis were divided into 3 groups and treated for 6 months with prednisolone, depot tetracosactrin, or indomethacin. Their whole body content of calcium, phosphorus, and nitrogen was measured before and after 3 and 6 months' treatment by in-vivo neutron activation analysis. No significant changes in these body elements were observed as a result of the treatments. The average amounts of calcium, phosphorus, and nitrogen were lower than normal in these patients, a finding consistent with the frequent observation of osteoporosis and muscle wasting in rheumatoid arthritis.

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References

    1. J Nucl Med. 1975 Mar;16(3):196-9 - PubMed
    1. J Appl Physiol. 1975 Mar;38(3):455-60 - PubMed
    1. Curr Med Res Opin. 1975;3(6):345-58 - PubMed
    1. Ann Rheum Dis. 1959 Mar;18(1):49-51; French transl 51-2; Spanish transl 52-3 - PubMed
    1. Ann Rheum Dis. 1952 Jun;11(2):97-111 - PubMed