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• An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice.

  Rohm M, Schäfer M, Laurent V, Üstünel BE, Niopek K, Algire C, Hautzinger O, Sijmonsma TP, Zota A, Medrikova D, Pellegata NS, Ryden M, Kulyte A, Dahlman I, Arner P, Petrovic N, Cannon B, Amri EZ, Kemp BE, Steinberg GR, Janovska P, Kopecky J, Wolfrum C, Blüher M, Berriel Diaz M, Herzig S. Rohm M, et al. Nat Med. 2016 Oct;22(10):1120-1130. doi: 10.1038/nm.4171. Epub 2016 Aug 29. Nat Med. 2016. PMID: 27571348
• Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis.

  Reznick RM, Zong H, Li J, Morino K, Moore IK, Yu HJ, Liu ZX, Dong J, Mustard KJ, Hawley SA, Befroy D, Pypaert M, Hardie DG, Young LH, Shulman GI. Reznick RM, et al. Cell Metab. 2007 Feb;5(2):151-6. doi: 10.1016/j.cmet.2007.01.008. Cell Metab. 2007. PMID: 17276357 Free PMC article.
• Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.

  Yan Y, Zhou XE, Novick SJ, Shaw SJ, Li Y, Brunzelle JS, Hitoshi Y, Griffin PR, Xu HE, Melcher K. Yan Y, et al. J Biol Chem. 2019 Jan 18;294(3):953-967. doi: 10.1074/jbc.RA118.004883. Epub 2018 Nov 26. J Biol Chem. 2019. PMID: 30478170 Free PMC article.
• CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations.

  Scott JW, Hawley SA, Green KA, Anis M, Stewart G, Scullion GA, Norman DG, Hardie DG. Scott JW, et al. J Clin Invest. 2004 Jan;113(2):274-84. doi: 10.1172/JCI19874. J Clin Invest. 2004. PMID: 14722619 Free PMC article.
• Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade.

  Hawley SA, Boudeau J, Reid JL, Mustard KJ, Udd L, Mäkelä TP, Alessi DR, Hardie DG. Hawley SA, et al. J Biol. 2003;2(4):28. doi: 10.1186/1475-4924-2-28. Epub 2003 Sep 24. J Biol. 2003. PMID: 14511394 Free PMC article.