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. 2000 Aug;59(8):583-6.
doi: 10.1136/ard.59.8.583.

Yttrium radiosynoviorthesis in the treatment of knee arthritis in rheumatoid arthritis: a systematic review

L L Heuft-Dorenbosch  1 , H C de Vet, S van der Linden
Affiliations

Yttrium radiosynoviorthesis in the treatment of knee arthritis in rheumatoid arthritis: a systematic review

L L Heuft-Dorenbosch et al. Ann Rheum Dis. 2000 Aug.

Abstract

Objective: To consider the question: How strong is the evidence in favour of yttrium synovectomy in chronic knee arthritis in patients with rheumatoid arthritis in comparison with placebo and intra-articular steroid treatment?

Methods: A systematic review of the literature was performed using Medline and the Embase database.

Results: Initially, seven papers were identified, but only two met the inclusion criteria. Neither study showed evidence in favour of yttrium synovectomy.

Conclusion: From the point of view of evidence based medicine it should be seriously questioned whether yttrium synovectomy deserves a place in clinical practice.

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