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Review
. 2000 Jul;33(7):503-10.
doi: 10.1021/ar990073r.

Elucidating a biological role for chromium at a molecular level

J B Vincent  1
Affiliations
Review

Elucidating a biological role for chromium at a molecular level

J B Vincent. Acc Chem Res. 2000 Jul.

Abstract

Chromium is an essential trace element for mammals and is required for maintenance of proper carbohydrate and lipid metabolism. However, elucidating its function at a molecular level has proved to be problematic. Recent research has revealed that the chromium-binding oligopeptide chromodulin may play a unique role in the autoamplification of insulin signaling. Attempts to develop chromium-containing nutritional supplements and therapeutics are described.

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