Review
doi: 10.1021/ar990073r.
Elucidating a biological role for chromium at a molecular level
Affiliations
- PMID: 10913239
- DOI: 10.1021/ar990073r
Item in Clipboard
Review
Elucidating a biological role for chromium at a molecular level
Acc Chem Res.
2000 Jul.
Abstract
Chromium is an essential trace element for mammals and is required for maintenance of proper carbohydrate and lipid metabolism. However, elucidating its function at a molecular level has proved to be problematic. Recent research has revealed that the chromium-binding oligopeptide chromodulin may play a unique role in the autoamplification of insulin signaling. Attempts to develop chromium-containing nutritional supplements and therapeutics are described.
Similar articles
-
The biochemistry of chromium.J Nutr. 2000 Apr;130(4):715-8. doi: 10.1093/jn/130.4.715. J Nutr. 2000. PMID: 10736319 Review.
-
Recent advances in the nutritional biochemistry of trivalent chromium.Proc Nutr Soc. 2004 Feb;63(1):41-7. doi: 10.1079/PNS2003315. Proc Nutr Soc. 2004. PMID: 15070438 Review.
-
The trail of chromium(III) in vivo from the blood to the urine: the roles of transferrin and chromodulin.J Biol Inorg Chem. 2001 Jun;6(5-6):608-17. doi: 10.1007/s007750100238. J Biol Inorg Chem. 2001. PMID: 11472024
-
The binding of trivalent chromium to low-molecular-weight chromium-binding substance (LMWCr) and the transfer of chromium from transferrin and chromium picolinate to LMWCr.J Biol Inorg Chem. 2000 Feb;5(1):129-36. doi: 10.1007/s007750050016. J Biol Inorg Chem. 2000. PMID: 10766445
-
Chromium: celebrating 50 years as an essential element?Dalton Trans. 2010 Apr 28;39(16):3787-94. doi: 10.1039/b920480f. Epub 2010 Feb 2. Dalton Trans. 2010. PMID: 20372701 Review.
Cited by
-
The Effects of Trivalent Lanthanide Cationization on the Electron Transfer Dissociation of Acidic Fibrinopeptide B and its Analogs.J Am Soc Mass Spectrom. 2016 Sep;27(9):1499-509. doi: 10.1007/s13361-016-1428-7. Epub 2016 Jun 13. J Am Soc Mass Spectrom. 2016. PMID: 27294379 Free PMC article.
-
Effects of acidic peptide size and sequence on trivalent praseodymium adduction and electron transfer dissociation mass spectrometry.J Mass Spectrom. 2017 Apr;52(4):218-229. doi: 10.1002/jms.3919. J Mass Spectrom. 2017. PMID: 28170125 Free PMC article.
-
Proteomic profiling of the endogenous peptides of MRSA and MSSA.PeerJ. 2021 Nov 24;9:e12508. doi: 10.7717/peerj.12508. eCollection 2021. PeerJ. 2021. PMID: 34900427 Free PMC article.
-
Associations between IVF outcomes and essential trace elements measured in follicular fluid and urine: a pilot study.J Assist Reprod Genet. 2017 Feb;34(2):253-261. doi: 10.1007/s10815-016-0853-7. Epub 2016 Dec 9. J Assist Reprod Genet. 2017. PMID: 27943108 Free PMC article.
-
Alternative Metal with an Alternative Mechanism for Metalloporphyrin-Enabled NO Reduction to N2O: A Combined Computational and Experimental Investigation of NO Reduction by Cr Porphyrin with Lewis Acid.Inorg Chem. 2025 Mar 31;64(12):6335-6345. doi: 10.1021/acs.inorgchem.5c00226. Epub 2025 Mar 18. Inorg Chem. 2025. PMID: 40098432
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
