doi: 10.1016/0092-8674(75)90172-5.
Replicating circular DNA molecules in yeast
- PMID: 1091361
- DOI: 10.1016/0092-8674(75)90172-5
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Replicating circular DNA molecules in yeast
Cell.
1975 Mar.
Abstract
The yeast Saccharomyces cerevisiae contains a class of small circular DNA molecules, approximately 2 mum in contour length (Sinclair et al., 1967). In this report, it is shown that these molecules replicate as double-branched circles, similar to those observed during replication of the bacteriophage lambda and Escherichia coli chromosomes. A normal rate of replication of these DNA circles requires the function of a nuclear gene, cdc 8.
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