[Evidence of abnormalities in net sodium and potassium fluxes in erythrocytes of patients with essential hypertension]
- PMID: 109228
[Evidence of abnormalities in net sodium and potassium fluxes in erythrocytes of patients with essential hypertension]
Abstract
A new and simple laboratory test for measuring net Na+ and K+ fluxes in Na+-loaded/K+-depleted human erythrocytes was developed and applied to hypertension. Moderate essential hypertension was characterized by a constant increase in net K+ influx; more severe cases showed a drop in net Na+ efflux. Na+ and K+ erythrocyte fluxes were found to be normal in hypertension of renal origin.