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Clinical Trial
. 1975 Apr 19;2(5963):119-20.
doi: 10.1136/bmj.2.5963.119.

Comparison of two methods of administering bronchodilator aerosol to asthmatic patients

Y F Choo-Kang, I W Grant
Clinical Trial

Comparison of two methods of administering bronchodilator aerosol to asthmatic patients

Y F Choo-Kang et al. Br Med J. .

Abstract

In 78 patients with chronic asthma the increase in forced expiratory volume in one second (FEV-1) after the administration by intermittent positive-pressure ventilation (I.P.P.V.) of 10 mg of salbutamol was compared with that recorded after the inhalation of a conventional dose (200 mug) from a pressurized canister. The mean increase was significantly greater after I.P.P.V. administration, and the superiority of this method was greatest in patients with the lowest pretreatment FEV-1.

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