Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1975 Mar;28(3):431-42.

Effect of Corynebacterium parvum on the class and subclass of antibody produced in the response of different strains of mice to sheep erythrocytes

G W Warr, K James
Comparative Study

Effect of Corynebacterium parvum on the class and subclass of antibody produced in the response of different strains of mice to sheep erythrocytes

G W Warr et al. Immunology. 1975 Mar.

Abstract

Several strains of mice were injected with sheep erythrocytes (SRBC) using C. parvum as adjuvant. The adjuvant effects on the amounts of class and subclass of antibody produced were ranked in the order IgG2b greater than IgG2a and IgM greater than IgG1. In addition, these effects were shown to vary depending on the time of administration of C. parvum relative to antigen. C parvum was shown to have no adjuvant effect on the response of congenitally athymic mice when given at the same time as the antigen, SRBC. On the basis of the reported observations it is suggested that certain of the adjuvant effects of C. parvum require T-cell function.

PubMed Disclaimer

References

    1. Ann Inst Pasteur (Paris). 1964 May;106:771-7 - PubMed
    1. Immunology. 1968 Jan;14(1):7-20 - PubMed
    1. Curr Top Microbiol Immunol. 1973;61:151-71 - PubMed
    1. Clin Exp Immunol. 1971 Jun;8(6):839-56 - PubMed
    1. Clin Exp Immunol. 1974 Dec;18(4):571-8 - PubMed

Publication types

LinkOut - more resources