T cell-dependent mediator in the immune response. III. The role of non-specific factor (NSF) in the in vitro immune response
- PMID: 1092612
- PMCID: PMC1445774
Item in Clipboard
T cell-dependent mediator in the immune response. III. The role of non-specific factor (NSF) in the in vitro immune response
Immunology.
1975 Mar.
Abstract
Evidence is presented which suggests that T cell-dependent nonspecific factor (NSF) cannot be the sole mediator of 'co-operation' for all types of thymus-dependent antibody response. NSF can replace the requirement for T cells in responses to hapten conjugated to particulate carriers, but cannot do so in responses to hapten conjugates of soluble thymus-dependent carriers.
Similar articles
-
Carrier and hapten functions in immune deviation. II. Role of hapten and carrier on the helper functions of the T cells.Immunology. 1975 Mar;28(3):553-9. Immunology. 1975. PMID: 47838 Free PMC article.
-
Cellular requirements for development of primary anti-hapten antibody responses in vitro.J Immunol. 1973 Jul;111(1):137-42. J Immunol. 1973. PMID: 4123367 No abstract available.
-
T cell-dependent mediator and B-cell clones.Immunology. 1975 Jun;28(6):1149-54. Immunology. 1975. PMID: 1093973 Free PMC article.
-
T cell-dependent suppression of an anti-hapten antibody response.Transplant Rev. 1975;26:130-69. doi: 10.1111/j.1600-065x.1975.tb00178.x. Transplant Rev. 1975. PMID: 52217 Review. No abstract available.
-
Auto-immune disease.Rheumatol Rehabil. 1976 Feb;15(1):1-9. doi: 10.1093/rheumatology/15.1.1. Rheumatol Rehabil. 1976. PMID: 814605 Review.
Cited by
-
The inter-relationship of antigenic structure, thymus-independence and adjuvanticity. IV. A general model for B-cell induction.Immunology. 1975 Mar;28(3):509-22. Immunology. 1975. PMID: 1092613 Free PMC article.
-
The role of H-2-linked genes in helper T cell function. VII. Expression of I region and immune response genes by B cells in bystander help assays.J Exp Med. 1980 Nov 1;152(5):1274-88. doi: 10.1084/jem.152.5.1274. J Exp Med. 1980. PMID: 6159447 Free PMC article.
-
Non-specific factor replaces T cells in an IgG response to soluble antigens.Immunology. 1977 Sep;33(3):321-9. Immunology. 1977. PMID: 302821 Free PMC article.
-
Antigen-non-specific T-cell factor in B-cell activation. Origin, biological properties and failure to show a relationship to H-2.Immunology. 1976 May;30(5):723-33. Immunology. 1976. PMID: 58834 Free PMC article.
-
Analysis of the response of B cells from CBA/N-defective mice to nonspecific T cell help.J Exp Med. 1981 Nov 1;154(5):1608-17. doi: 10.1084/jem.154.5.1608. J Exp Med. 1981. PMID: 6975350 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources