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Review
. 2000 Jul;9(4):335-40.
doi: 10.1097/00041552-200007000-00003.

Epithelial calcium channel: gate-keeper of active calcium reabsorption

J G Hoenderop  1 , D Müller, M Suzuki, C H van Os, R J Bindels
Affiliations
Review

Epithelial calcium channel: gate-keeper of active calcium reabsorption

J G Hoenderop et al. Curr Opin Nephrol Hypertens. 2000 Jul.

Abstract

The epithelial calcium channel present in the apical membrane of 1,25-dihydroxyvitamin D3-responsive nephron segments represents the first member of a new family of calcium channels. This review covers the distinctive properties of this highly calcium-selective channel and highlights the implications for our understanding of the process of calcium reabsorption.

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