Performance of the OptiMAL malaria antigen capture dipstick for malaria diagnosis and treatment monitoring at the Hospital for Tropical Diseases, London
- PMID: 10929047
- DOI: 10.1046/j.1365-2141.2000.01974.x
Performance of the OptiMAL malaria antigen capture dipstick for malaria diagnosis and treatment monitoring at the Hospital for Tropical Diseases, London
Abstract
We report here the sensitivity and specificity of OptiMAL for the diagnosis of acute malaria in patients presenting to the Hospital for Tropical Diseases (HTD), a tertiary referral centre for Tropical and Infectious diseases. A sensitivity of 95.3% and a specificity of 100% for Plasmodium falciparum and a sensitivity of 96% and a specificity of 100% for Plasmodium vivax was obtained. The ability to follow the course of the parasitaemia using OptiMAL during treatment and its significance for use in areas where expert microscopy is not available is discussed.
Comment in
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Will the high rates of post-treatment sexual stage parasitaemia seen in malaria-endemic areas make the optiMAL antigen test unreliable in predicting malaria treatment outcome?Br J Haematol. 2001 Apr;113(1):255-7. doi: 10.1046/j.1365-2141.2001.02673-2.x. Br J Haematol. 2001. PMID: 11328311 No abstract available.
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Following the course of malaria treatment by detecting parasite lactate dehydrogenase enzyme.Br J Haematol. 2001 May;113(2):558-9. doi: 10.1046/j.1365-2141.2001.02782.x. Br J Haematol. 2001. PMID: 11380433 No abstract available.
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