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Review
. 2000 Aug;106(3):329-33.
doi: 10.1172/JCI10761.

Interactions between insulin resistance and insulin secretion in the development of glucose intolerance

M K Cavaghan  1 , D A Ehrmann, K S Polonsky
Affiliations
Review

Interactions between insulin resistance and insulin secretion in the development of glucose intolerance

M K Cavaghan et al. J Clin Invest. 2000 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Plasma insulin concentrations (a) and insulin secretion rates (b) in response to molar increments in the plasma glucose concentration during a graded glucose infusion in insulin-resistant (dashed line) and insulin-sensitive (solid line) groups. Reprinted with permission (4).
Figure 2
Figure 2
Dose-response relationships between glucose and insulin secretory rate (ISR) after overnight fast in control subjects (CON; filled circles), normoglycemic subjects with family history of non–insulin-dependent diabetes mellitus (FDR, first-degree relative; open squares), subjects with nondiagnostic oral glucose tolerance test (NDX; filled triangles), subjects with impaired glucose tolerance (IGT; open diamonds), and subjects with non–insulin-dependent diabetes mellitus (NIDDM; open triangles). BMI, body mass index. Reprinted with permission (21).
See this image and copyright information in PMC

References

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