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. 2000 Aug;7(8):648-52.
doi: 10.1038/77943.

Structure of the DNA binding domain of E. coli SSB bound to ssDNA

S Raghunathan  1 , A G Kozlov, T M Lohman, G Waksman
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Structure of the DNA binding domain of E. coli SSB bound to ssDNA

S Raghunathan et al. Nat Struct Biol. 2000 Aug.

Abstract

The structure of the homotetrameric DNA binding domain of the single stranded DNA binding protein from Escherichia coli (Eco SSB) bound to two 35-mer single stranded DNAs was determined to a resolution of 2.8 A. This structure describes the vast network of interactions that results in the extensive wrapping of single stranded DNA around the SSB tetramer and suggests a structural basis for its various binding modes.

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